Modifications in Aortic Stiffness After Endovascular or Open Aortic Repair: A Systematic Review and Meta-Analysis

Increased aortic stiffness (AoS) has been recognised as a risk factor in the development of cardiovascular disease. The aim this systematic review and meta-analysis was to assess impact repair on AoS. PubMed, Scopus, Web Science were searched systematically for relevant studies evaluating consequences endovascular open Preferred Reporting Items Systematic Reviews Meta-Analysis Protocols (PRISMA-P) statement followed perform research process. Papers containing data AoS before after both thoracic (TEVAR) abdominal (EVAR) repair, well surgical (OSR), included detailed evaluation. A fixed effects model used analysis. Newcastle–Ottawa Scale calculated each study. first article cluster comprised 367 papers. After removal duplicates adoption inclusion/exclusion criteria, 14 articles remained, 13 which selected meta-analysis. Ten analysed EVAR three TEVAR. Five papers case control studies, with OSR adopted four these comparator. Several graft types group. increased TEVAR EVAR, terms pulse wave velocity (PWV), even though several spatial levels measurement modalities adopted. No differences described OSR, although no pooled could be analysed. demonstrated significant increase (PWV). Although heterogeneity low number available limit strength results, highlights potential deleterious endograft role system further are needed achieve robust evidence. Further improve mutual interaction between aorta endograft, minimising their native wall properties.